Physiological and genetic adaptations of metabolism allow us to react appropriately to different food components and diets. Our research groups investigate the influence of nutrition on energy balance, i.e. the balance between energy intake and energy turnover.
Our research projects deal with various aspects of nutritional and metabolic physiology. We investigate both mouse models and mammalian cells in culture, applying a broad methodological spectrum of physiology, cell biology and molecular biology. At the physiological level, the components of the energy budget in mice are quantified under different nutritional conditions. At the molecular level, the function of mitochondria (the power plants of a cell) in cultured cells and isolated cell organelles is analyzed.