Severin Lechner

Position: PhD student
Room: 005
Category: PhD student
Phone: 0 8161 714202
Email: severin.lechner[at]tum.de

Publications

2022

  • Glas, Carina; Naydenova, Eli; Lechner, Severin; Wössner, Nathalie; Yang, Liu; Dietschreit, Johannes C.B.; Sun, Hongyan; Jung, Manfred; Kuster, Bernhard; Ochsenfeld, Christian; Bracher, Franz: Development of hetero-triaryls as a new chemotype for subtype-selective and potent Sirt5 inhibition. European Journal of Medicinal Chemistry 240, 2022, 114594 mehr…
  • Lechner, Severin; Malgapo, Martin Ian P.; Grätz, Christian; Steimbach, Raphael R.; Baron, Agnes; Rüther, Patrick; Nadal, Simon; Stumpf, Carmen; Loos, Christina; Ku, Xin; Prokofeva, Polina; Lautenbacher, Ludwig; Heimburg, Tino; Würf, Vivian; Meng, Chen; Wilhelm, Mathias; Sippl, Wolfgang; Kleigrewe, Karin; Pauling, Josch K.; Kramer, Karl; Miller, Aubry K.; Pfaffl, Michael W.; Linder, Maurine E.; Kuster, Bernhard; Médard, Guillaume: Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target. Nature Chemical Biology, 2022 mehr…
  • Steimbach, Raphael R.; Herbst-Gervasoni, Corey J.; Lechner, Severin; Stewart, Tracy Murray; Klinke, Glynis; Ridinger, Johannes; Géraldy, Magalie N. E.; Tihanyi, Gergely; Foley, Jackson R.; Uhrig, Ulrike; Kuster, Bernhard; Poschet, Gernot; Casero, Robert A., Jr.; Médard, Guillaume; Oehme, Ina; Christianson, David W.; Gunkel, Nikolas; Miller, Aubry K.: Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. Journal of the American Chemical Society 144 (41), 2022, 18861-18875 mehr…