Affinity matrices for subproteome enrichment

Kinobeads™ is a kinase-binding matrix that can be used to measure quantatively the binding interaction of a compound with more than 300 different kinases at the same time. The resulting information can elucidate a compound's mode of action and therefore indicate which diseases it might be used against, or point to potential side effects. Kinobeads™ can replace or complement the current established methods for screening and selectivity profiling of kinase inhibitors to over- come some of the challenges in kinase drug discovery.

Besides further developing Kinobeads™ we focus on the development of other affinity matrices for the enrichment of subproteomes, e.g. important functional protein classes.