The EU-OPENSCREEN-DRIVE Chemoproteomics and Mass Spectrometry Imaging (MSI) Call 2021 aims at increasing the understanding of mechanisms of action by which a tool or small molecule hit/lead compound exerts its pharmacological effect. The users are offered access to target-based and phenotype-based workflows, proteomics and related advanced mass spectrometry-based technologies, with focus on MSI. EU-OPENSCREEN-DRIVE chemistry partner sites together with partners with proven track-records in probe development, target deconvolution and MSI will support at least 3 successful applicants providing collaboration on target identification and compound disposition studies. Under this call, applicants will have the opportunity to access a broad range of experimental approaches through different chemical proteomic workflows for samples of bacterial and mammalian origin or in whole organisms (e.g. multicellular parasites). Preference will be given to projects using MSI and/or involving synthesis of chemical probes for affinity-based target identification.
You can find more information about the call here!